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WHAT DISEASES MAY CAUSE SWELLING OF THE LYMPH NODES
Lymph nodes are found in the groin at the juncture of the leg and the body, as well as in other areas of the body, such as the neck and the armpits. They are part of the lymphatic system, through which circulate cells of the immune system that are important in fighting off infection and cancer. Basically any infection in the genital area can result in swelling of the lymph nodes in the groin. Once lymph nodes swell, they usually do not return to their normal size. Swollen lymph nodes are usually rubbery in texture and do not hurt. This list is by no means all inclusive, but it summarizes the most common causes of lymph node swelling. An examination by a health care provider is necessary to make a definitive diagnosis.
Cancer in the genital area. Because the lymph nodes in the groin receive drainage from all the pelvic structures, cancer in any of the genital organs may cause the lymph nodes in that area to swell. Lymph nodes enlarged as the result of a malignancy are usually hard and not moveable. Lymph node swelling in young adults is rarely caused by cancer; more often it is the result of an infection. Lymph node swelling that results from infection usually subsides considerably when the infection is treated. A lymph node biopsy—in which a small piece of tissue is removed and then examined under the microscope—can be performed to rule out cancer if there is a question.
Infection in the genital area. Any genital infection can cause lymph node swelling in the genital area. This includes bacterial infections such as gonorrhea, chlamydia, lymphogranuloma venereum, chancroid, syphilis, and donovanosis, as well as the syndromes PID and MPC in women and NGU in men. The viral infection herpes and the protozoan infection trichomoniasis can also cause lymph node swelling. Even a bladder infection can result in groin node swelling.
Conditions that can cause lymph node swelling throughout the body. Systemic (whole-body) infections such as mononucleosis, HFV, and secondary syphilis, as well as malignancies such as lymphoma (a cancer of the lymph nodes), can cause swelling in lymph nodes throughout the body (neck, armpits, and other areas in addition to the groin). Other symptoms are usually also present.
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